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Moving Protein PEGylation from an Art to a Data Science
[Image: see text] PEGylation is a well-established and clinically proven half-life extension strategy for protein delivery. Protein modification with amine-reactive poly(ethylene glycol) (PEG) generates heterogeneous and complex bioconjugate mixtures, often composed of several PEG positional isomers...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501918/ https://www.ncbi.nlm.nih.gov/pubmed/35994522 http://dx.doi.org/10.1021/acs.bioconjchem.2c00262 |