Overcoming the Drawbacks of Sulpiride by Means of New Crystal Forms

This study aims at developing new multicomponent crystal forms of sulpiride, an antipsychotic drug. The main goal was to improve its solubility since it belongs to class IV of the BCS. Nine new adducts were obtained by combining the active pharmaceutical ingredient with acid coformers: a salt cocrys...

Descripción completa

Detalles Bibliográficos
Autores principales: Birolo, Rebecca, Bravetti, Federica, Bordignon, Simone, D’Abbrunzo, Ilenia, Mazzeo, Paolo P., Perissutti, Beatrice, Bacchi, Alessia, Chierotti, Michele R., Gobetto, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501926/
https://www.ncbi.nlm.nih.gov/pubmed/36145502
http://dx.doi.org/10.3390/pharmaceutics14091754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501926/
https://www.ncbi.nlm.nih.gov/pubmed/36145502
http://dx.doi.org/10.3390/pharmaceutics14091754

Ejemplares similares