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Overcoming the Drawbacks of Sulpiride by Means of New Crystal Forms
This study aims at developing new multicomponent crystal forms of sulpiride, an antipsychotic drug. The main goal was to improve its solubility since it belongs to class IV of the BCS. Nine new adducts were obtained by combining the active pharmaceutical ingredient with acid coformers: a salt cocrys...
Autores principales: | Birolo, Rebecca, Bravetti, Federica, Bordignon, Simone, D’Abbrunzo, Ilenia, Mazzeo, Paolo P., Perissutti, Beatrice, Bacchi, Alessia, Chierotti, Michele R., Gobetto, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501926/ https://www.ncbi.nlm.nih.gov/pubmed/36145502 http://dx.doi.org/10.3390/pharmaceutics14091754 |
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