Neuroprotective Effects of a New Derivative of Chlojaponilactone B against Oxidative Damaged Induced by Hydrogen Peroxide in PC12 Cells

A new sesquiterpenoid (1) was obtained by hydrogenating Chlojaponilactone B. The structure of 1 was elucidated according to a combination of NMR, HRESIMS, and NOE diffraction data. The treatment of H(2)O(2) in a PC12 cell model was used to evaluate the antioxidant activity of 1. An MMT assay showed...

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Detalles Bibliográficos
Autores principales: Ye, Shaoxia, Wen, Qiyin, Zhu, Longping, Qian, Chunguo, Yang, Depo, Zhao, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501937/
https://www.ncbi.nlm.nih.gov/pubmed/36144782
http://dx.doi.org/10.3390/molecules27186049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501937/
https://www.ncbi.nlm.nih.gov/pubmed/36144782
http://dx.doi.org/10.3390/molecules27186049

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