Transport and Permeation Properties of Dapivirine: Understanding Potential Drug-Drug Interactions

The dapivirine (DPV) vaginal ring was developed by the nonprofit International Partnership for Microbicides (IPM) for reducing the risk of HIV infection. A clinical study (IPM 028) showed that concomitant use of the DPV ring and miconazole (MIC) altered DPV pharmacokinetic profile. In this work, we...

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Detalles Bibliográficos
Autores principales: Zheng, Ruohui, Valicherla, Guru R., Zhang, Junmei, Nuttall, Jeremy, Silvera, Peter, Marshall, Leslie J., Empey, Philip E., Rohan, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501983/
https://www.ncbi.nlm.nih.gov/pubmed/36145696
http://dx.doi.org/10.3390/pharmaceutics14091948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501983/
https://www.ncbi.nlm.nih.gov/pubmed/36145696
http://dx.doi.org/10.3390/pharmaceutics14091948

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