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Transport and Permeation Properties of Dapivirine: Understanding Potential Drug-Drug Interactions

The dapivirine (DPV) vaginal ring was developed by the nonprofit International Partnership for Microbicides (IPM) for reducing the risk of HIV infection. A clinical study (IPM 028) showed that concomitant use of the DPV ring and miconazole (MIC) altered DPV pharmacokinetic profile. In this work, we...

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Detalles Bibliográficos
Autores principales:	Zheng, Ruohui, Valicherla, Guru R., Zhang, Junmei, Nuttall, Jeremy, Silvera, Peter, Marshall, Leslie J., Empey, Philip E., Rohan, Lisa C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501983/ https://www.ncbi.nlm.nih.gov/pubmed/36145696 http://dx.doi.org/10.3390/pharmaceutics14091948

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