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Immune Responses to Gene Editing by Viral and Non-Viral Delivery Vectors Used in Retinal Gene Therapy

Inherited retinal diseases (IRDs) are a leading cause of blindness in industrialized countries, and gene therapy is quickly becoming a viable option to treat this group of diseases. Gene replacement using a viral vector has been successfully applied and advanced to commercial use for a rare group of...

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Detalles Bibliográficos
Autores principales: Ren, Duohao, Fisson, Sylvain, Dalkara, Deniz, Ail, Divya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502120/
https://www.ncbi.nlm.nih.gov/pubmed/36145721
http://dx.doi.org/10.3390/pharmaceutics14091973