Robust and efficient single-cell Hi-C clustering with approximate k-nearest neighbor graphs

MOTIVATION: Hi-C technology provides insights into the 3D organization of the chromatin, and the single-cell Hi-C method enables researchers to gain knowledge about the chromatin state in individual cell levels. Single-cell Hi-C interaction matrices are high dimensional and very sparse. To cluster t...

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Detalles Bibliográficos
Autores principales: Wolff, Joachim, Backofen, Rolf, Grüning, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502147/
https://www.ncbi.nlm.nih.gov/pubmed/34021764
http://dx.doi.org/10.1093/bioinformatics/btab394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502147/
https://www.ncbi.nlm.nih.gov/pubmed/34021764
http://dx.doi.org/10.1093/bioinformatics/btab394

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