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Robust and efficient single-cell Hi-C clustering with approximate k-nearest neighbor graphs
MOTIVATION: Hi-C technology provides insights into the 3D organization of the chromatin, and the single-cell Hi-C method enables researchers to gain knowledge about the chromatin state in individual cell levels. Single-cell Hi-C interaction matrices are high dimensional and very sparse. To cluster t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502147/ https://www.ncbi.nlm.nih.gov/pubmed/34021764 http://dx.doi.org/10.1093/bioinformatics/btab394 |