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BERTMHC: improved MHC–peptide class II interaction prediction with transformer and multiple instance learning

MOTIVATION: Increasingly comprehensive characterization of cancer-associated genetic alterations has paved the way for the development of highly specific therapeutic vaccines. Predicting precisely the binding and presentation of peptides to major histocompatibility complex (MHC) alleles is an import...

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Detalles Bibliográficos
Autores principales: Cheng, Jun, Bendjama, Kaïdre, Rittner, Karola, Malone, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502151/
https://www.ncbi.nlm.nih.gov/pubmed/34096999
http://dx.doi.org/10.1093/bioinformatics/btab422