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DetectIS: a pipeline to rapidly detect exogenous DNA integration sites using DNA or RNA paired-end sequencing data

MOTIVATION: Recombinant DNA technology is widely used for different applications in biology, medicine and bio-technology. Viral transduction and plasmid transfection are among the most frequently used techniques to generate recombinant cell lines. Many of these methods result in the random integrati...

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Detalles Bibliográficos
Autores principales: Grassi, Luigi, Harris, Claire, Zhu, Jie, Hardman, Colin, Hatton, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502153/
https://www.ncbi.nlm.nih.gov/pubmed/33978747
http://dx.doi.org/10.1093/bioinformatics/btab366