Formation Mechanism of Inter-Crosslink in DNA by Nitrogen Oxides Pollutants through A Diazonium Intermediate

Outdoor air pollution is a mixture of multiple atmospheric pollutants, among which nitrogen oxide (NOx) stands out due to its association with several diseases. NOx reactivity can conduct to DNA damage as severe as interstrand crosslinks (ICL) formation, that in turn is able to block DNA replication...

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Detalles Bibliográficos
Autores principales: Hernandez-Haro, Noemi, Solis-Calero, Christian, Casasnovas, Rodrigo, Morell, Christophe, Grand, Andre, Frau, Juan, Ortega-Castro, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502170/
https://www.ncbi.nlm.nih.gov/pubmed/36142522
http://dx.doi.org/10.3390/ijms231810621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502170/
https://www.ncbi.nlm.nih.gov/pubmed/36142522
http://dx.doi.org/10.3390/ijms231810621

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