Alpha-Mangostin as a New Therapeutic Candidate for Concanavalin A-Induced Autoimmune Hepatitis: Impact on the SIRT1/Nrf2 and NF-κB Crosstalk

Alpha-mangostin (α-MN) is a xanthone obtained from Garcinia mangostana that has diverse anti-oxidative and anti-inflammatory potentials. However, its pharmacological activity against autoimmune hepatitis (AIH) has not been investigated before. Concanavalin A (Con A) was injected into mice to induce...

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Detalles Bibliográficos
Autores principales: Shehata, Ahmed M., Elbadawy, Hossein M., Ibrahim, Sabrin R. M., Mohamed, Gamal A., Elsaed, Wael M., Alhaddad, Aisha A., Ahmed, Nishat, Abo-Haded, Hany, El-Agamy, Dina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502360/
https://www.ncbi.nlm.nih.gov/pubmed/36145841
http://dx.doi.org/10.3390/plants11182441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502360/
https://www.ncbi.nlm.nih.gov/pubmed/36145841
http://dx.doi.org/10.3390/plants11182441

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