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Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors

Cyclin-dependent kinase 5 (Cdk5) is an atypical proline-directed serine/threonine protein kinase well-characterized for its role in the central nervous system rather than in the cell cycle. Indeed, its dysregulation has been strongly implicated in the progression of synaptic dysfunction and neurodeg...

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Detalles Bibliográficos
Autores principales: Di Stefano, Miriana, Galati, Salvatore, Ortore, Gabriella, Caligiuri, Isabella, Rizzolio, Flavio, Ceni, Costanza, Bertini, Simone, Bononi, Giulia, Granchi, Carlotta, Macchia, Marco, Poli, Giulio, Tuccinardi, Tiziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502400/
https://www.ncbi.nlm.nih.gov/pubmed/36142566
http://dx.doi.org/10.3390/ijms231810653