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Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors

Cyclin-dependent kinase 5 (Cdk5) is an atypical proline-directed serine/threonine protein kinase well-characterized for its role in the central nervous system rather than in the cell cycle. Indeed, its dysregulation has been strongly implicated in the progression of synaptic dysfunction and neurodeg...

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Detalles Bibliográficos
Autores principales:	Di Stefano, Miriana, Galati, Salvatore, Ortore, Gabriella, Caligiuri, Isabella, Rizzolio, Flavio, Ceni, Costanza, Bertini, Simone, Bononi, Giulia, Granchi, Carlotta, Macchia, Marco, Poli, Giulio, Tuccinardi, Tiziano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502400/ https://www.ncbi.nlm.nih.gov/pubmed/36142566 http://dx.doi.org/10.3390/ijms231810653

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