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The Interplay between Aquaporin-1 and the Hypoxia-Inducible Factor 1α in a Lipopolysaccharide-Induced Lung Injury Model in Human Pulmonary Microvascular Endothelial Cells

Aquaporin-1 (AQP1), a water channel, and the hypoxia-inducible factor 1α (HIF1A) are implicated in acute lung injury responses, modulating among others pulmonary vascular leakage. We hypothesized that the AQP1 and HIF1A systems interact, affecting mRNA, protein levels and function of AQP1 in human p...

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Detalles Bibliográficos
Autores principales: Keskinidou, Chrysi, Lotsios, Nikolaos S., Vassiliou, Alice G., Dimopoulou, Ioanna, Kotanidou, Anastasia, Orfanos, Stylianos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502402/
https://www.ncbi.nlm.nih.gov/pubmed/36142499
http://dx.doi.org/10.3390/ijms231810588