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INGAP-Peptide Variants as a Novel Therapy for Type 1 Diabetes: Effect on Human Islet Insulin Secretion and Gene Expression

Islet transplantation offers a long-term cure for Type 1 Diabetes (T1D), freeing patients from daily insulin injections. Therapeutic peptides have shown potential to increase the insulin output of pancreatic islets, maximizing the impact of grafted cells. The islet neogenesis-associated protein (ING...

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Detalles Bibliográficos
Autores principales: Porter, James M., Guerassimoff, Léa, Castiello, Francisco Rafael, Charette, André, Tabrizian, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502412/
https://www.ncbi.nlm.nih.gov/pubmed/36145580
http://dx.doi.org/10.3390/pharmaceutics14091833