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Regioselective Synthesis, Structural Characterization, and Antiproliferative Activity of Novel Tetra-Substituted Phenylaminopyrazole Derivatives

A small library of highly functionalized phenylaminopyrazoles, bearing different substituents at position 1, 3, and 4 of the pyrazole ring, was prepared by the one-pot condensation of active methylene reagents, phenylisothiocyanate, and substituted hydrazine (namely, methyl- and benzyl-hydrazine). T...

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Detalles Bibliográficos
Autores principales: Lusardi, Matteo, Profumo, Aldo, Rotolo, Chiara, Iervasi, Erika, Rosano, Camillo, Spallarossa, Andrea, Ponassi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502416/
https://www.ncbi.nlm.nih.gov/pubmed/36144549
http://dx.doi.org/10.3390/molecules27185814