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Type 2 Diabetes Risk and Lipid Metabolism Related to the Pleiotropic Effects of an ABCB1 Variant: A Chinese Family-Based Cohort Study

The single nucleotide polymorphism (SNP) rs4148727 in ABCB1 (encoding p-glycoprotein) is associated with lipid levels; however, its association with type 2 diabetes (T2DM) and its the genetic correlation with lipid profiles and T2DM are unclear. We included 2300 participants from 593 families. A gen...

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Detalles Bibliográficos
Autores principales: Wu, Junhui, Wang, Xiaowen, Chen, Hongbo, Yang, Ruotong, Yu, Huan, Wu, Yiqun, Hu, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502507/
https://www.ncbi.nlm.nih.gov/pubmed/36144279
http://dx.doi.org/10.3390/metabo12090875