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Comprehensive evaluation of the safety and immunogenicity of a gene-deleted variant pseudorabies virus attenuated vaccine

Pseudorabies virus (PRV) variant infections have caused a substantial economic impact on swine production in the absence of new powerful candidate vaccines. In this study, we developed and evaluated a gene-deleted variant pseudorabies virus (PRV)-attenuated vaccine, PRV GX-ΔTK/IES, in which the gene...

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Detalles Bibliográficos
Autores principales: Li, Ling, Du, Yongfeng, Zhang, Yanbin, Li, Pengyu, Liu, Xinyue, Zhang, Xin, Li, Jing, Zhang, Tong, Li, Xin, Xiao, Dong, Liu, Peng, Qi, Peng, Xiao, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502647/
https://www.ncbi.nlm.nih.gov/pubmed/36138470
http://dx.doi.org/10.1186/s13567-022-01091-4