Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors

Allosteric integrase (IN) inhibitors (ALLINIs), which are promising preclinical compounds that engage the lens epithelium-derived growth factor (LEDGF)/p75 binding site on IN, can inhibit different aspects of human immunodeficiency virus 1 (HIV-1) replication. During the late phase of replication, A...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Parmit Kumar, Li, Wen, Bedwell, Gregory J., Fadel, Hind J., Poeschla, Eric M., Engelman, Alan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502684/
https://www.ncbi.nlm.nih.gov/pubmed/36146690
http://dx.doi.org/10.3390/v14091883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502684/
https://www.ncbi.nlm.nih.gov/pubmed/36146690
http://dx.doi.org/10.3390/v14091883

Ejemplares similares