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Hibiscus sabdariffa Extract Protects HaCaT Cells against Phenanthrene-Induced Toxicity through the Regulation of Constitutive Androstane Receptor/Pregnane X Receptor Pathway

Phenanthrene (Phe) exposure is associated with skin ageing, cardiotoxicity and developmental defects. Here, we investigated the mode of Phe toxicity in human keratinocytes (HaCaT cells) and the attenuation of toxicity on pre-treatment (6 h) with ethanol extract of Hibiscus sabdariffa calyxes (HS). C...

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Detalles Bibliográficos
Autores principales: Malar, Dicson Sheeja, Prasanth, Mani Iyer, Verma, Kanika, Prasansuklab, Anchalee, Tencomnao, Tewin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502750/
https://www.ncbi.nlm.nih.gov/pubmed/36145217
http://dx.doi.org/10.3390/nu14183829