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Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes

Microbial dysbiosis has emerged as a modulator of oncogenesis and response to therapy, particularly in lung cancer. Here, we investigate the evolution of the gut and lung microbiomes following exposure to a tobacco carcinogen. We performed 16S rRNA-Seq of fecal and lung samples collected prior to an...

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Detalles Bibliográficos
Autores principales: Finnicum, Casey T., Rahal, Zahraa, Hassane, Maya, Treekitkarnmongkol, Warapen, Sinjab, Ansam, Morris, Rhiannon, Liu, Yuejiang, Tang, Elizabeth L., Viet, Sarah, Petersen, Jason L., Lorenzi, Philip L., Tan, Lin, Petrosino, Joseph, Hoffman, Kristi L., Fujimoto, Junya, Moghaddam, Seyed Javad, Kadara, Humam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502774/
https://www.ncbi.nlm.nih.gov/pubmed/36142843
http://dx.doi.org/10.3390/ijms231810930