Quantitative RT-PCR Assays for Quantification of Undesirable Mutants in the Novel Type 2 Oral Poliovirus Vaccine

Emergence of mutations is an inherent property of RNA viruses with several implications for their replication, pathogenesis, and evolutionary adaptation. Oral poliovirus vaccine (OPV), developed by Albert Sabin, is composed of live attenuated polioviruses of three serotypes that can revert to neurov...

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Detalles Bibliográficos
Autores principales: Manukyan, Hasmik, Wahid, Rahnuma, Ansari, Azeem, Tritama, Erman, Macadam, Andrew, Konz, John, Chumakov, Konstantin, Laassri, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502871/
https://www.ncbi.nlm.nih.gov/pubmed/36146473
http://dx.doi.org/10.3390/vaccines10091394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502871/
https://www.ncbi.nlm.nih.gov/pubmed/36146473
http://dx.doi.org/10.3390/vaccines10091394

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