Renal Transcriptome and Metabolome in Mice with Principal Cell-Specific Ablation of the Tsc1 Gene: Derangements in Pathways Associated with Cell Metabolism, Growth and Acid Secretion

Tuberous sclerosis complex (TSC) is caused by mutations in the hamartin (TSC1) or tuberin (TSC2) genes. Using a mouse model of TSC renal cystogenesis that we have previously described, the current studies delineate the metabolic changes in the kidney and their relation to alterations in renal gene e...

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Detalles Bibliográficos
Autores principales: Zahedi, Kamyar, Barone, Sharon, Brooks, Marybeth, Murray Stewart, Tracy, Casero, Robert A., Soleimani, Manoocher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502912/
https://www.ncbi.nlm.nih.gov/pubmed/36142537
http://dx.doi.org/10.3390/ijms231810601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502912/
https://www.ncbi.nlm.nih.gov/pubmed/36142537
http://dx.doi.org/10.3390/ijms231810601

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