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Transcriptional Activation of Ecdysone-Responsive Genes Requires H3K27 Acetylation at Enhancers

The steroid hormone ecdysone regulates insect development via its nuclear receptor (the EcR protein), which functions as a ligand-dependent transcription factor. The EcR regulates target gene expression by binding to ecdysone response elements (EcREs) in their promoter or enhancer regions. Its role...

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Detalles Bibliográficos
Autores principales: Cheng, Dong, Dong, Zhaoming, Lin, Ping, Shen, Guanwang, Xia, Qingyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502983/
https://www.ncbi.nlm.nih.gov/pubmed/36142704
http://dx.doi.org/10.3390/ijms231810791