In Vitro Safety, Off-Target and Bioavailability Profile of the Antiviral Compound Silvestrol

We characterized the in vitro safety and bioavailability profile of silvestrol, a compound effective against various viruses, such as corona- and Ebolaviruses, with an EC(50) value of about 5 nM. The cytotoxic profile of silvestrol was assessed in various cancer cell lines, as well as the mutagenic...

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Detalles Bibliográficos
Autores principales: Schiffmann, Susanne, Gunne, Sandra, Ulshöfer, Thomas, Henke, Marina, Roser, Luise A., Schneider, Ann-Kathrin, Cinatl, Jindrich, Thomas, Dominique, Schreiber, Yannick, Wagner, Pia Viktoria, Grünweller, Arnold, Parnham, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502993/
https://www.ncbi.nlm.nih.gov/pubmed/36145307
http://dx.doi.org/10.3390/ph15091086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9502993/
https://www.ncbi.nlm.nih.gov/pubmed/36145307
http://dx.doi.org/10.3390/ph15091086

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