Determining Ligand and Ion-Induced Conformational Changes in Serotonin Transporter with Its Fluorescent Substrates

Conformational changes are fundamental events in the transport mechanism. The serotonin transporter (SERT) catalyzes reuptake of the neurotransmitter serotonin after its release by serotonergic neurons and is the molecular target for antidepressant drugs and psychostimulants. Despite significant pro...

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Detalles Bibliográficos
Autores principales: Li, Mu, Chen, Qingyang, Zhang, Yuan-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503009/
https://www.ncbi.nlm.nih.gov/pubmed/36142837
http://dx.doi.org/10.3390/ijms231810919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503009/
https://www.ncbi.nlm.nih.gov/pubmed/36142837
http://dx.doi.org/10.3390/ijms231810919

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