Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats

The aim of this work was to study the healing activity of amitriptyline (Amitrip) in rat diabetic wounds. A nanoformula of the drug was prepared as Amitrip-based biodegradable PEG-PLGA self-assembled nanoparticles (Amitrip-NPs) with a mean particle size of 67.4 nm. An in vivo investigation was condu...

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Detalles Bibliográficos
Autores principales: Asfour, Hani Z., Alhakamy, Nabil A., Ahmed, Osama A. A., Fahmy, Usama A., El-moselhy, Mohamed A., Rizg, Waleed Y., Alghaith, Adel F., Eid, Basma G., Abdel-Naim, Ashraf B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503070/
https://www.ncbi.nlm.nih.gov/pubmed/36145540
http://dx.doi.org/10.3390/pharmaceutics14091792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503070/
https://www.ncbi.nlm.nih.gov/pubmed/36145540
http://dx.doi.org/10.3390/pharmaceutics14091792

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