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Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats

The aim of this work was to study the healing activity of amitriptyline (Amitrip) in rat diabetic wounds. A nanoformula of the drug was prepared as Amitrip-based biodegradable PEG-PLGA self-assembled nanoparticles (Amitrip-NPs) with a mean particle size of 67.4 nm. An in vivo investigation was condu...

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Detalles Bibliográficos
Autores principales:	Asfour, Hani Z., Alhakamy, Nabil A., Ahmed, Osama A. A., Fahmy, Usama A., El-moselhy, Mohamed A., Rizg, Waleed Y., Alghaith, Adel F., Eid, Basma G., Abdel-Naim, Ashraf B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503070/ https://www.ncbi.nlm.nih.gov/pubmed/36145540 http://dx.doi.org/10.3390/pharmaceutics14091792

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