Computational Prediction of Inhibitors and Inducers of the Major Isoforms of Cytochrome P450

Human cytochrome P450 enzymes (CYPs) are heme-containing monooxygenases. This superfamily of drug-metabolizing enzymes is responsible for the metabolism of most drugs and other xenobiotics. The inhibition of CYPs may lead to drug–drug interactions and impair the biotransformation of drugs. CYP induc...

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Detalles Bibliográficos
Autores principales: Rudik, Anastassia, Dmitriev, Alexander, Lagunin, Alexey, Filimonov, Dmitry, Poroikov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503090/
https://www.ncbi.nlm.nih.gov/pubmed/36144612
http://dx.doi.org/10.3390/molecules27185875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503090/
https://www.ncbi.nlm.nih.gov/pubmed/36144612
http://dx.doi.org/10.3390/molecules27185875

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