Cheminformatics Identification of Phenolics as Modulators of Penicillin-Binding Protein 2a of Staphylococcus aureus: A Structure–Activity-Relationship-Based Study

The acquisition of penicillin-binding protein (PBP) 2a in resistant strains of Staphylococcus aureus allows for the continuous production of cell walls even after the inactivation of intrinsic PBPs. Thus, the discovery of novel therapeutics with enhanced modulatory activity on PBP2a is crucial, and...

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Detalles Bibliográficos
Autores principales: Aribisala, Jamiu Olaseni, Sabiu, Saheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503099/
https://www.ncbi.nlm.nih.gov/pubmed/36145565
http://dx.doi.org/10.3390/pharmaceutics14091818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503099/
https://www.ncbi.nlm.nih.gov/pubmed/36145565
http://dx.doi.org/10.3390/pharmaceutics14091818

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