New Insights into Ion Channels: Predicting hERG-Drug Interactions

Drug-induced long QT syndrome can be a very dangerous side effect of existing and developmental drugs. In this work, a model proposed two decades ago addressing the ion specificity of potassium channels is extended to the human ether-à-gogo gene (hERG). hERG encodes the protein that assembles into t...

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Detalles Bibliográficos
Autor principal: Wempe, Michael Fitzpatrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503154/
https://www.ncbi.nlm.nih.gov/pubmed/36142644
http://dx.doi.org/10.3390/ijms231810732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503154/
https://www.ncbi.nlm.nih.gov/pubmed/36142644
http://dx.doi.org/10.3390/ijms231810732

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