Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells

(1) Background: 2-Methoxyestradiol (2ME) is a metabolite of estrogens and possesses promising anti-proliferative and cytotoxic activities. However, it suffers unfavorable pharmacokinetic characteristics such as absorption after oral administration. The aim of this study was to prepare an optimized 2...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Qahtani, Salwa D., Bin-Melaih, Hawazen H., Atiya, Eman M., Fahmy, Usama A., Binmahfouz, Lenah S., Neamatallah, Thikryat, Al-Abbasi, Fahad A., Abdel-Naim, Ashraf B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503162/
https://www.ncbi.nlm.nih.gov/pubmed/36143405
http://dx.doi.org/10.3390/life12091369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503162/
https://www.ncbi.nlm.nih.gov/pubmed/36143405
http://dx.doi.org/10.3390/life12091369

Ejemplares similares