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Epigenetic and transcriptomic alterations in offspring born to women with type 1 diabetes (the EPICOM study)

BACKGROUND: Offspring born to women with pregestational type 1 diabetes (T1DM) are exposed to an intrauterine hyperglycemic milieu and has an increased risk of metabolic disease later in life. In this present study, we hypothesize that in utero exposure to T1DM alters offspring DNA methylation and g...

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Detalles Bibliográficos
Autores principales: Knorr, Sine, Skakkebæk, Anne, Just, Jesper, Johannsen, Emma B., Trolle, Christian, Vang, Søren, Lohse, Zuzana, Bytoft, Birgitte, Damm, Peter, Højlund, Kurt, Jensen, Dorte M., Gravholt, Claus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503228/
https://www.ncbi.nlm.nih.gov/pubmed/36138412
http://dx.doi.org/10.1186/s12916-022-02514-x