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Detecting associated genes for complex traits shared across East Asian and European populations under the framework of composite null hypothesis testing

BACKGROUND: Detecting trans-ethnic common associated genetic loci can offer important insights into shared genetic components underlying complex diseases/traits across diverse continental populations. However, effective statistical methods for such a goal are currently lacking. METHODS: By leveragin...

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Detalles Bibliográficos
Autores principales: Qiao, Jiahao, Shao, Zhonghe, Wu, Yuxuan, Zeng, Ping, Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503281/
https://www.ncbi.nlm.nih.gov/pubmed/36138484
http://dx.doi.org/10.1186/s12967-022-03637-8