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Detecting associated genes for complex traits shared across East Asian and European populations under the framework of composite null hypothesis testing
BACKGROUND: Detecting trans-ethnic common associated genetic loci can offer important insights into shared genetic components underlying complex diseases/traits across diverse continental populations. However, effective statistical methods for such a goal are currently lacking. METHODS: By leveragin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503281/ https://www.ncbi.nlm.nih.gov/pubmed/36138484 http://dx.doi.org/10.1186/s12967-022-03637-8 |