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Microneedle Delivery of an Adjuvanted Microparticulate Vaccine Induces High Antibody Levels in Mice Vaccinated against Coronavirus

This ‘proof-of-concept’ study aimed to test the microparticulate vaccine delivery system and a transdermal vaccine administration strategy using dissolving microneedles (MN). For this purpose, we formulated poly(lactic-co-glycolic) acid (PLGA) microparticles (MP) encapsulating the inactivated canine...

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Detalles Bibliográficos
Autores principales: Vijayanand, Sharon, Patil, Smital, Joshi, Devyani, Menon, Ipshita, Braz Gomes, Keegan, Kale, Akanksha, Bagwe, Priyal, Yacoub, Shadi, Uddin, Mohammad N., D’Souza, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503342/
https://www.ncbi.nlm.nih.gov/pubmed/36146568
http://dx.doi.org/10.3390/vaccines10091491