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Combined Ramipril and Black Seed Oil Dosage Forms Using Bioactive Self-Nanoemulsifying Drug Delivery Systems (BIO-SNEDDSs)

Purpose: Ramipril (RMP)—an angiotensin-converting enzyme (ACE) inhibitor—and thymoquinone (THQ) suffer from poor oral bioavailability. Developing a combined liquid SNEDDS that comprises RMP and black seed oil (as a natural source of THQ) could lead to several formulations and therapeutic benefits. M...

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Detalles Bibliográficos
Autores principales: Shahba, Ahmad Abdul-Wahhab, Sherif, Abdelrahman Y., Elzayat, Ehab M., Kazi, Mohsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503356/
https://www.ncbi.nlm.nih.gov/pubmed/36145341
http://dx.doi.org/10.3390/ph15091120