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The Antiviral Effects of 2-Deoxy-D-glucose (2-DG), a Dual D-Glucose and D-Mannose Mimetic, against SARS-CoV-2 and Other Highly Pathogenic Viruses

Viral infection almost invariably causes metabolic changes in the infected cell and several types of host cells that respond to the infection. Among metabolic changes, the most prominent is the upregulated glycolysis process as the main pathway of glucose utilization. Glycolysis activation is a comm...

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Detalles Bibliográficos
Autores principales: Pająk, Beata, Zieliński, Rafał, Manning, John Tyler, Matejin, Stanislava, Paessler, Slobodan, Fokt, Izabela, Emmett, Mark R., Priebe, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503362/
https://www.ncbi.nlm.nih.gov/pubmed/36144664
http://dx.doi.org/10.3390/molecules27185928