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5-Arylidenerhodanines as P-gp Modulators: An Interesting Effect of the Carboxyl Group on ABCB1 Function in Multidrug-Resistant Cancer Cells

Multidrug resistance (MDR) is considered one of the major mechanisms responsible for the failure of numerous anticancer and antiviral chemotherapies. Various strategies to overcome the MDR phenomenon have been developed, and one of the most attractive research directions is focused on the inhibition...

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Detalles Bibliográficos
Autores principales: Żesławska, Ewa, Tejchman, Waldemar, Kincses, Annamária, Spengler, Gabriella, Nitek, Wojciech, Żuchowski, Grzegorz, Szymańska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503420/
https://www.ncbi.nlm.nih.gov/pubmed/36142724
http://dx.doi.org/10.3390/ijms231810812