Role of the Cysteine in R3 Tau Peptide in Copper Binding and Reactivity

Tau is a widespread neuroprotein that regulates the cytoskeleton assembly. In some neurological disorders, known as tauopathies, tau is dissociated from the microtubule and forms insoluble neurofibrillary tangles. Tau comprises four pseudorepeats (R1–R4), containing one (R1, R2, R4) or two (R3) hist...

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Detalles Bibliográficos
Autores principales: Bacchella, Chiara, Gentili, Silvia, Mozzi, Sara Ida, Monzani, Enrico, Casella, Luigi, Tegoni, Matteo, Dell’Acqua, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503722/
https://www.ncbi.nlm.nih.gov/pubmed/36142637
http://dx.doi.org/10.3390/ijms231810726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503722/
https://www.ncbi.nlm.nih.gov/pubmed/36142637
http://dx.doi.org/10.3390/ijms231810726

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