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Role of the Cysteine in R3 Tau Peptide in Copper Binding and Reactivity
Tau is a widespread neuroprotein that regulates the cytoskeleton assembly. In some neurological disorders, known as tauopathies, tau is dissociated from the microtubule and forms insoluble neurofibrillary tangles. Tau comprises four pseudorepeats (R1–R4), containing one (R1, R2, R4) or two (R3) hist...
Autores principales: | Bacchella, Chiara, Gentili, Silvia, Mozzi, Sara Ida, Monzani, Enrico, Casella, Luigi, Tegoni, Matteo, Dell’Acqua, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503722/ https://www.ncbi.nlm.nih.gov/pubmed/36142637 http://dx.doi.org/10.3390/ijms231810726 |
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