R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization

Progressive rod-cone degeneration (PRCD) is a photoreceptor outer segment (OS) disc-specific protein essential for maintaining OS structures while contributing to rhodopsin packaging densities and distribution in disc membranes. Previously, we showed PRCD undergoing palmitoylation at the sole cystei...

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Detalles Bibliográficos
Autores principales: Myers, Boyden, Sechrest, Emily R., Hamner, Gabrielle, Motipally, Sree I., Murphy, Joseph, Kolandaivelu, Saravanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503786/
https://www.ncbi.nlm.nih.gov/pubmed/36142714
http://dx.doi.org/10.3390/ijms231810802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503786/
https://www.ncbi.nlm.nih.gov/pubmed/36142714
http://dx.doi.org/10.3390/ijms231810802

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