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R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization
Progressive rod-cone degeneration (PRCD) is a photoreceptor outer segment (OS) disc-specific protein essential for maintaining OS structures while contributing to rhodopsin packaging densities and distribution in disc membranes. Previously, we showed PRCD undergoing palmitoylation at the sole cystei...
Autores principales: | Myers, Boyden, Sechrest, Emily R., Hamner, Gabrielle, Motipally, Sree I., Murphy, Joseph, Kolandaivelu, Saravanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503786/ https://www.ncbi.nlm.nih.gov/pubmed/36142714 http://dx.doi.org/10.3390/ijms231810802 |
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