Vitamin E TPGS-Poloxamer Nanoparticles Entrapping a Novel PI3Kα Inhibitor Potentiate Its Activity against Breast Cancer Cell Lines

N-(2-fluorphenyl)-6-chloro-4-hydroxy-2-quinolone-3-carboxamide (R19) is a newly synthesized phosphatidylinositol 3-kinase alpha (PI3Kα) inhibitor with promising activity against cancer cells. The purpose of this study was to develop a polymeric nanoparticle (NP) formulation for R19 to address its po...

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Detalles Bibliográficos
Autores principales: Sunoqrot, Suhair, Aliyeh, Sundos, Abusulieh, Samah, Sabbah, Dima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503791/
https://www.ncbi.nlm.nih.gov/pubmed/36145724
http://dx.doi.org/10.3390/pharmaceutics14091977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503791/
https://www.ncbi.nlm.nih.gov/pubmed/36145724
http://dx.doi.org/10.3390/pharmaceutics14091977

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