Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs

Infection of pigs with the African swine fever virus (ASFV) leads to a devastating hemorrhagic disease with a high mortality of up to 100%. In this study, a CD2v gene deletion was introduced to a genotype IX virus from East Africa, ASFV-Kenya-IX-1033 (ASFV-Kenya-IX-1033-∆CD2v), to investigate whethe...

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Detalles Bibliográficos
Autores principales: Hemmink, Johanneke D., Khazalwa, Emmanuel M., Abkallo, Hussein M., Oduor, Bernard, Khayumbi, Jeremiah, Svitek, Nicholas, Henson, Sonal P., Blome, Sandra, Keil, Günther, Bishop, Richard P., Steinaa, Lucilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503863/
https://www.ncbi.nlm.nih.gov/pubmed/36146726
http://dx.doi.org/10.3390/v14091917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503863/
https://www.ncbi.nlm.nih.gov/pubmed/36146726
http://dx.doi.org/10.3390/v14091917

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