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Monitoring of Ex Vivo Cyclosporin a Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics

Therapeutic drug monitoring (TDM) of calcineurin inhibitors (i.e., tacrolimus and cyclosporin A) is standard of care after solid organ transplantation. Although the incidence of acute rejection has strongly decreased, there are still many patients who experience severe side effects or rejection afte...

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Detalles Bibliográficos
Autores principales: in ’t Veld, Aliede E., Jansen, Manon A. A., Huisman, Bertine W., Schoonakker, Mascha, de Kam, Marieke L., Moes, Dirk Jan A. R., van Poelgeest, Mariëtte I. E., Burggraaf, Jacobus, Moerland, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503885/
https://www.ncbi.nlm.nih.gov/pubmed/36145707
http://dx.doi.org/10.3390/pharmaceutics14091958