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A Bivalent Trans-Amplifying RNA Vaccine Candidate Induces Potent Chikungunya and Ross River Virus Specific Immune Responses

Alphaviruses such as the human pathogenic chikungunya virus (CHIKV) and Ross River virus (RRV) can cause explosive outbreaks raising public health concerns. However, no vaccine or specific antiviral treatment is yet available. We recently established a CHIKV vaccine candidate based on trans-amplifyi...

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Detalles Bibliográficos
Autores principales: Schmidt, Christin, Hastert, Florian D., Gerbeth, Julia, Beissert, Tim, Sahin, Ugur, Perkovic, Mario, Schnierle, Barbara S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503900/
https://www.ncbi.nlm.nih.gov/pubmed/36146452
http://dx.doi.org/10.3390/vaccines10091374