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In Silico Studies Reveal Peramivir and Zanamivir as an Optimal Drug Treatment Even If H7N9 Avian Type Influenza Virus Acquires Further Resistance

An epidemic of avian type H7N9 influenza virus, which took place in China in 2013, was enhanced by a naturally occurring R294K mutation resistant against Oseltamivir at the catalytic site of the neuraminidase. To cope with such drug-resistant neuraminidase mutations, we applied the molecular docking...

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Detalles Bibliográficos
Autores principales: Sarukhanyan, Edita, Shanmugam, Tipack Ayothyapattanam, Dandekar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503969/
https://www.ncbi.nlm.nih.gov/pubmed/36144655
http://dx.doi.org/10.3390/molecules27185920