The hEag1 K(+) Channel Inhibitor Astemizole Stimulates Ca(2+) Deposition in SaOS-2 and MG-63 Osteosarcoma Cultures

The hEag1 (Kv10.1) K(+) channel is normally found in the brain, but it is ectopically expressed in tumor cells, including osteosarcoma. Based on the pivotal role of ion channels in osteogenesis, we tested whether pharmacological modulation of hEag1 may affect osteogenic differentiation of osteosarco...

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Detalles Bibliográficos
Autores principales: Mészáros, Beáta, Csoti, Agota, Szanto, Tibor G., Telek, Andrea, Kovács, Katalin, Toth, Agnes, Volkó, Julianna, Panyi, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504018/
https://www.ncbi.nlm.nih.gov/pubmed/36142445
http://dx.doi.org/10.3390/ijms231810533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504018/
https://www.ncbi.nlm.nih.gov/pubmed/36142445
http://dx.doi.org/10.3390/ijms231810533

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